Manager, Antibody Characterization

New Manager, Antibody Characterization USA - Portland, OR Apply Twist Bioscience is seeking a highly motivated and enthusiastic Manager, Antibody Characterization to join our dynamic Operations Team. This is an exciting opportunity to lead a critical function within a fast-paced, high-growth synthetic biology environment. The ideal candidate will thrive on the challenge of building new product lines while enforcing the rigor and accountability essential for delivering world-class, high-quality products to both internal and external customers. Onsite - 5 Days per week - Wilsonville, Oregon. What You’ll Be Doing:  Manage, train, and mentor production team members, fostering a collaborative and high-performing laboratory environment. Overseeing, running, and troubleshooting antibody characterization experiments using advanced analytical techniques (e.g. BLI and SPR) in a variety of formats to evaluate binding kinetics, ligand blocking, and binning. Act as the primary point of contact for shift Manufacturing Associates and Specialists, ensuring the team adheres to the plan of record. Provide guidance, oversee priority decisions, and lead troubleshooting efforts for production issues as they arise. Establish and track Key Performance Indicators (KPIs) to drive production efficiency and meet department goals. Model capacity and recommend high-throughput workflow options and staffing plans based on demand forecasts. Drive operational excellence by identifying and implementing Continuous Process Improvement (CPI) initiatives to increase capacity, reduce Turnaround Time (TAT), and lower Cost of Goods Sold (COGS). Lead complex technical investigations and risk assessments related to processes, including resolving customer incidents. Maintain thorough, accurate, and detailed documentation of all work in batch records, databases, or other approved formats, including problems and deviations. Develop and revise Standard Operating Procedures (SOPs), work instructions, and training documents for the characterization of proteins/antibodies. Ensure the team operates in compliance with necessary quality standards. Collaborate with internal and external customers on protein production projects Work closely with the Director and support functions to evaluate opportunities for product line improvements, contributing to Twist's strategic vision. Lead cross-functional projects, including running recurring status meetings and managing assignments across teams in the US, Europe, and Asia. What You'll Bring to the Team B.S. or M.S. degree in Biology, Biochemistry, Immunology, Process Engineering, or a related field. 5+ years of experience in the biotech/pharmaceutical industry, preferably involving the characterization of diagnostic and/or therapeutic antibodies. Strong understanding of antibody discovery, preferably focusing on assay development and protein characterization Previous experience with BLI, SPR, and ELISA strongly preferred. A proven track record of successfully developing and manufacturing protein-based commercial products. Demonstrated scientific leadership, mentoring, and organizational skills in managing direct reports and overseeing external collaborations (e.g., CROs). Deep expertise in basic synthetic/molecular biology skills, including Mammalian Cell Culturing, Transfection, Buffer Exchange, and molecular biology workflows. Excellent project management skills: proficient with timeline development, project tracking, and the ability to efficiently manage and prioritize multiple projects. Exceptional attention to detail, organizational, and record-keeping skills. Familiarity with PLM, ERP, and MES management systems is a plus. #LI-LK1   Create a Job Alert Interested in building your career at Twist Bioscience? Get future opportunities sent straight to your email. Create alert Apply for this job * indicates a required field Autofill with MyGreenhouse First Name * Last Name * Email * Phone Country Phone Resume/CV Attach Attach Dropbox Google Drive Enter manually Enter manually Accepted file types: pdf, doc, docx, txt, rtf Cover Letter Attach Attach Dropbox Google Drive Enter manually Enter manually Accepted file types: pdf, doc, docx, txt, rtf LinkedIn Profile Website Voluntary Self-Identification For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file. As set forth in Twist Bioscience’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law. Gender Select... Are you Hispanic/Latino? Select... Race & Ethnicity Definitions If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows: A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability. A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service. An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense. An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985. Veteran Status Select... Voluntary Self-Identification of Disability Form CC-305 Page 1 of 1 OMB Control Number 1250-0005 Expires 04/30/2026 Why are you being asked to complete this form? We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years. Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp . How do you know if you have a disability? A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to: Alcohol or other substance use disorder (not currently using drugs illegally) Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS Blind or low vision Cancer (past or present) Cardiovascular or heart disease Celiac disease Cerebral palsy Deaf or serious difficulty hearing Diabetes Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders Epilepsy or other seizure disorder Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome Intellectual or developmental disability Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD Missing limbs or partially missing limbs Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS) Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities Partial or complete paralysis (any cause) Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema Short stature (dwarfism) Traumatic brain injury Disability Status Select... PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete. Submit application