Senior Bioinformatics Scientist

What if the work you did every day could impact the lives of people you know? Or all of humanity?At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.Senior Bioinformatics Scientist - Protein Design Cambridge Hub & Hybrid We are seeking a talented and driven Senior Bioinformatics Scientist - Computational Biology (Protein Design) – to join our dynamic interdisciplinary protein engineering group that is responsible for the development of novel protein reagents for high-throughput sequencing.In return, Illumina's employee benefits are industry-leading and include flexible time off, private medical insurance, compassion, and care time off, leisure travel insurance, pension, employee stock purchasing program, volunteer time off and much more! The role The successful candidate will initiate, execute, and analyze research in the area of Computational Biology / Bioinformatics applied to high-throughput sequencing, collaboratively working with multidisciplinary teams.The role is based at Cambridge, England. This is an exciting opportunity to be a part of Illumina’s continued growth.Your Responsibilities include, but are not limited to:Develop and apply tailored bioinformatics tools and pipelines to design, engineer, and/or discover novel enzymes.Enable enzyme activity and/or property predictions using state-of-the-art AI/ML approaches.Evaluate application, development, and implementation of novel computational methods to leverage protein sequence, structure, and/or experimental data for enzyme engineering.Participate in multi-disciplinarily protein engineering projects and interact with engineers, chemists, biophysicists, and protein scientists, to deliver protein variants with desired properties.All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional task and responsibilities.Education, Experience & Attributes required:Ph.D. in computational chemistry, computational biology, bioinformatics, computer science or related fields, or equivalent work & educational experience.Solid programming skills in at least one of the major programming languages (e.g., C/C++, Python, R).In-depth knowledge of protein sequence or structure modelling, protein-ligand interaction predictions and/or molecular simulations.Extensive understanding of AI/ML methods and good proficiency in model development using modern deep learning packages (e.g. PyTorch).Strong fundamentals in statistical modelling, algorithm design, data analysis, and/or visualization methods.Excellent verbal and written communication skills.Collaborative, open and self-aware, team player, and able to rapidly integrate into cross functional teams.Highly motivated individual with proven ability in thinking innovatively and the proven track record of productive research and development.Preferred experiences and attributesExperience with experiments within protein engineering, e.g. directed-evolution, high-throughput screening.Experience in using one or more commonly used molecular modelling software, e.g. Rosetta.Knowledge of best software development practices and code version control, e.g. Git.Knowledge of UNIX environment and shell scripting.Experience with high-performance computing, job schedulers, and/or GPU hardware.Broad knowledge of bioinformatics, genomics, and/or proteomics database, tools, and/or algorithms.Knowledge of biochemistry, enzymology, and/or molecular biology.Familiarity with next generation sequencing technologies, tools, and/or workflows.Does this sound like you? Apply today and we’ll be back in touch! Illumina believes that everyone has the ability to make an impact, and we are proud to be an equal opportunities employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.