Associate Scientist, Cell Therapy

About Metagenomi Metagenomi is a gene editing company committed to developing potentially curative therapeutics by leveraging a proprietary toolbox of next-generation gene editing systems to accurately edit DNA where current technologies cannot. Our metagenomics-powered discovery platform and analytical expertise reveal novel cellular machinery sourced from otherwise unknown organisms. We adapt and forge these naturally evolved systems into powerful gene editing systems that are ultra-small, extremely efficient, highly specific and have a decreased risk of immune response. These systems fuel our pipeline of novel medicines and can be leveraged by partners. Our goal is to revolutionize gene editing for the benefit of patients around the world.  "Whether it's the biological diversity of our gene editing systems or the people that help discover them, Metagenomi celebrates the diversity of life. This is achieved through a compassionate culture that acknowledges the dimensions of our diversity.  We know that when people feel a sense of inclusion and belonging in the workplace, they have a safe space to bring creativity and innovation to everything they do. We are intentional about building and maintaining a culture where people are valued and respected, there is equity in opportunities, and our respective opinions and differences matter.”   -Metagenomi Culture Committee   We are hiring a Senior Research Associate/Associate Scientist  on our growing Immunology and Pharmacology, Cell Therapy team. Reporting to a Senior Scientist, this position will contribute to our in vitro biology research by supporting the development of in vitro and ex vivo cell-based assays.  This role is based in Emeryville, California.  How you’ll contribute:  Support the development of in vitro and ex vivo cell-based assays to assess the functionality of isolated and engineered primary immune cells Support primary T-cell culture and process optimization Independently execute and analyze multi-color flow cytometry studies for primary cell phenotypic and functional characterization Support development of multiple projects across various cell vehicles and indications Work cross-functionally with Cell Therapy Functional Genomics, Gene Editing, and Process Development teams Prepare accurate and timely data summaries, contribute to writing of reports, and present findings to team. Must haves:    BS and/or MS in biological sciences and at least six years of relevant industry experience Broad knowledge of immuno-oncology and autoimmunity, hands-on experience in FACS-based cell sorting Familiarity with engineering immune cells using genome editing technologies such as CRISPR Proficient ability to independently execute, troubleshoot, and optimize cell-based assay development including proliferation assays, culture assays, and high-throughput assay execution Proficiency in designing and running multi-color flow cytometry panels, including analysis and interpretation Experience in techniques including ELISA, cytokine detection (Luminex or MSD), plate-reader-based assays Broad expertise in primary mammalian cell culture techniques and a working knowledge of cell biology/immunology Extensive experience handling human biological samples and primary immune cells Experience in lentiviral transduction and cell line development Excellent oral and written communication skills; superb organizational and time management skills ​​Highly collaborative, flexible, team-oriented, and considerate of the needs of others Self-motivated and thrives in a fast-moving, results-oriented startup environment with urgent deadlines California Pay Transparency Disclosure: This position is classified as an exempt salaried position under the Federal Labor Standards Act.  The anticipated base salary range for this position will be $100,000 -$125,000.  You will also be eligible to receive equity, bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on location, skill level, years and depth of relevant experience, and education.  #LI-NG1   What makes Metagenomi a unique place to work? We are passionate about developing technologies derived from microbial-rich ecosystems that have the power to enable therapeutic development and the potential to cure devastating disease. We have cultivated an amazing culture that values teamwork, curiosity, scientific rigor, and fun. We have a strong commitment to work/life balance, host a weekly employee happy hour and events, provide catered lunches and endless snacks, and more!  We offer competitive compensation including a market-benchmarked salary, annual target bonus potential, pre-IPO equity, and a comprehensive benefits plan, including 401(k) with company matching, a retirement safe harbor plan, and other perks.   At Metagenomi, we know that our people drive our success. We are an equal-opportunity employer and believe in and value diversity and inclusion. Metagenomi provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term careers. Metagenomi does not discriminate on the basis of race, color, religion, sexual orientation, gender, age, physical or mental disability, or any other status protected under federal, state, or local law. Please note, all candidates must be authorized to work in the United States.   Applicants/Employees have rights under various State and Federal Employment Laws, including without limitation: Family & Medical Leave Act  Equal Employment Opportunity Commission Employee Polygraph Protection Act  California Family Rights Act  California Fair Employment and Housing Act Notice to agencies: Our in-house Talent Acquisition Team manages all employment opportunities at Metagenomi. Agencies and independent recruiters must be approved as a vendor by Metagenomi’s Talent Acquisition team. To protect the interests of all parties, Metagenomi will not accept unsolicited resumes, profiles, or biographies. Any unsolicited resumes sent to Metagenomi will be considered referrals and the property of Metagenomi.