Bioengineer/Scientist II, Cell Therapy Process Development

About Metagenomi Metagenomi is a gene editing company committed to developing potentially curative therapeutics by leveraging a proprietary toolbox of next-generation gene editing systems to accurately edit DNA where current technologies cannot. Our metagenomics-powered discovery platform and analytical expertise reveal novel cellular machinery sourced from otherwise unknown organisms. We adapt and forge these naturally evolved systems into powerful gene editing systems that are ultra-small, extremely efficient, highly specific and have a decreased risk of immune response. These systems fuel our pipeline of novel medicines and can be leveraged by partners. Our goal is to revolutionize gene editing for the benefit of patients around the world.  "Whether it's the biological diversity of our gene editing systems or the people that help discover them, Metagenomi celebrates the diversity of life. This is achieved through a compassionate culture that acknowledges the dimensions of our diversity.  We know that when people feel a sense of inclusion and belonging in the workplace, they have a safe space to bring creativity and innovation to everything they do. We are intentional about building and maintaining a culture where people are valued and respected, there is equity in opportunities, and our respective opinions and differences matter.”   -Metagenomi Culture Committee   We are hiring a Bioengineer/Scientist II, Cell Therapy Process Development, to join our rapidly growing Cell Therapy team. While reporting to the Vice President, Cell Therapy Development, this position will contribute to the development and implementation of Cell Therapy Manufacturing processes. This role will be based in Emeryville, California How you’ll contribute:  Responsible for  DOE (Design of Experiment ), CAR T/TCR T cell therapy drugs process development (scale up, automation, and close system).  Improvement of process reliability, safety, cost-effectiveness, scalability, and compliance.   Generation of process models, author and review of detailed process flow diagrams (DPFD) - data summaries, analysis, presentations.      Must haves:    PhD with at least two years (or Masters with at least four years) of immunology and/or bioengineering industry experience in cell therapy process development Experience in cell therapy process development and establishing cell therapy manufacturing processes Demonstrated capability to conduct and document complex manufacturing processes and solid understanding of GMP and FDA guidelines Proven experience in the transfer of technologies/processes Familiarity with flow cytometry and other cell-based characterization assays (cytokine release and cytolytic assays)  Advanced proficiency/technical expertise w in using bioreactors, cell washers, closed harvest systems, and aseptic fill & finish systems Strong interpersonal, written, and oral communication skills A solution and team-oriented mindset, the ability to manage multiple priorities simultaneously, and a drive to make an impact California Pay Transparency Disclosure: This position is classified as an  exempt salaried  position under the Federal Labor Standards Act.  The anticipated base salary range for this position will be $135,000 to $150,000.  You will also be eligible to receive equity, bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on location, skill level, years and depth of relevant experience, and education.  #LI-NG1   What makes Metagenomi a unique place to work? We are passionate about developing technologies derived from microbial-rich ecosystems that have the power to enable therapeutic development and the potential to cure devastating disease. We have cultivated an amazing culture that values teamwork, curiosity, scientific rigor, and fun. We have a strong commitment to work/life balance, host a weekly employee happy hour and events, provide catered lunches and endless snacks, and more!  We offer competitive compensation including a market-benchmarked salary, annual target bonus potential, pre-IPO equity, and a comprehensive benefits plan, including 401(k) with company matching, a retirement safe harbor plan, and other perks.   At Metagenomi, we know that our people drive our success. We are an equal-opportunity employer and believe in and value diversity and inclusion. Metagenomi provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term careers. Metagenomi does not discriminate on the basis of race, color, religion, sexual orientation, gender, age, physical or mental disability, or any other status protected under federal, state, or local law. Please note, all candidates must be authorized to work in the United States.   Applicants/Employees have rights under various State and Federal Employment Laws, including without limitation: Family & Medical Leave Act  Equal Employment Opportunity Commission Employee Polygraph Protection Act  California Family Rights Act  California Fair Employment and Housing Act Notice to agencies: Our in-house Talent Acquisition Team manages all employment opportunities at Metagenomi. Agencies and independent recruiters must be approved as a vendor by Metagenomi’s Talent Acquisition team. To protect the interests of all parties, Metagenomi will not accept unsolicited resumes, profiles, or biographies. Any unsolicited resumes sent to Metagenomi will be considered referrals and the property of Metagenomi.